Multiple Walled Primary Package with Phase Change Material

A container for a temperature sensitive product, such as a pharmaceutical compound, includes an inner vessel and an outer shell. When the inner vessel is contained in the outer shell, a chamber adapted to receive a phase change material is defined between an inner vessel wall and an outer shell wall. A container may also include multiple chambers defined by multiple walls, with different phase change materials disposed in different chambers. A cap, such as a child-proof cap, may be used to secure the contents of the container.