专利类型:
相变材料专利导航
公开（公告）号:
WO1998014058A1
申请日:
1997-09-29
申请局:
US
摘要:
The combination of trehalose and dimethyl sulfoxide is an unusually effective cryoprotectant for islets and islet-like cell clusters, as well as platelets. Islets and ICCs, when cooled through the thermotropic phase transition in the presence of this combination of treatment agents and then returned to physiologic temperature, retain their functionality. Likewise, platelets can be similarly cooled and warmed without undergoing premature activation. In general, trehalose can be incorporated into eukaryotic cells in general by suspending the cells in a trehalose solution and either cooling or warming the solution through the thermotropic transition of the cells.
原始专利权人:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
当前专利权人:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA